人乳腺導(dǎo)管癌MDA-MB-435S
??【編號(hào)】:MDA-MB-435S ??【名稱】:人乳腺導(dǎo)管癌MDA-MB-435S ??【規(guī)格】:株 ??【價(jià)格】:1800 ![]() MDA-MB-435S人乳腺導(dǎo)管癌
描述:MDA-MB-435S是一種紡錘形的細(xì)胞,1976年由其親本(435)中篩選得到。435是從31歲的轉(zhuǎn)移性乳腺導(dǎo)管腺癌女性患者胸水中分離得到。 當(dāng)用熒光染料對(duì)微管蛋白進(jìn)行染色時(shí)親本細(xì)胞顯現(xiàn)散布特征(II型)。 最近通過cDNA陣列研究表明,親本(MDA-MB-435)可歸入黑素瘤起源。
動(dòng)物種別:人
性別:女
組織來源:乳腺; 乳房; 導(dǎo)管; 導(dǎo)管癌; 胸腺滲出液
形態(tài):紡錘形
培養(yǎng)基和添加劑:L-15培養(yǎng)基(GIBCO,貨號(hào)41300039)和0.01mg/ml胰島素,90%;優(yōu)質(zhì)胎牛血清,10%。 氣相:空氣,100%。 溫度:37攝氏度。
供應(yīng)限制:A。僅供研究之用。
REFERENCE:Brinkley BR , et al. Variations in cell form and cytoskeleton in human breast carcinoma cells in vitro. Cancer Res. 40: 3118-3129, 1980. PubMed: 7000337 Siciliano MJ , et al. Mutually exclusive genetic signatures of human breast tumor cell lines with a common chromosomal marker. Cancer Res. 39: 919-922, 1979. PubMed: 427779 Cailleau R , et al. Long-term human breast carcinoma cell lines of metastatic origin: preliminary characterization. In Vitro 14: 911-915, 1978. PubMed: 730202 Sheng S , et al. Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells. Proc. Natl. Acad. Sci. USA 93: 11669-11674, 1996. PubMed: 8876194 Zhu X , et al. Cell cycle-dependent modulation of telomerase activity in tumor cells. Proc. Natl. Acad. Sci. USA 93: 6091-6095, 1996. PubMed: 8650224 Ross DT , et al. Systematic variation in gene expression patterns in human cancer cell lines. Nature Genetics 24: 227-235, 2000. PubMed: 10700174 Ellison G , et al. Further evidence to support the melanocytic origin of MDA-MB-435. Mol. Pathol. 55: 294-299, 2002.
中文名稱:人乳腺導(dǎo)管癌
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